Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31429008 | 0.84 | HSD17B10 (0.58) | HSD17B10HPGDNPC1ALDH1A1NPSR1 | |
| SCHEMBL31428758 | 0.79 | PKM (0.50) | HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31428679 | 0.78 | HSD17B10 (0.60) | HSD17B10HPGDNPC1ALDH1A1NPSR1 | |
| SCHEMBL31428628 | 0.77 | HSD17B10 (0.52) | HSD17B10HPGDNPC1ALDH1A1NPSR1 | |
| SCHEMBL31428499 | 0.76 | L3MBTL3 (0.45) | HPGDL3MBTL1 | |
| SCHEMBL31428690 | 0.76 | SCN9A (0.44) | HPGDNPC1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL31428689 | 0.76 | SCN9A (0.44) | HPGDNPC1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL31428939 | 0.74 | HSD17B10 (0.52) | HSD17B10HPGDNPC1ALDH1A1NPSR1 | |
| SCHEMBL31428541 | 0.74 | L3MBTL3 (0.57) | ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL24975816 | 0.74 | HPGD (0.49) | HPGDNPC1RAB9ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | HSD17B10 4107/4885HPGD 4233/4885NPC1 3237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.