Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GPR183 | P32249 | 1/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.47 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.47 |
| ▸ | ITGAL | P20701 | 1/20 | 0.47 |
| ▸ | SELE | P16581 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428688 | 0.91 | RAB9A (0.55) | RAB9ANPC1TDP1ALDH1A1HPGD | |
| SCHEMBL31429114 | 0.85 | RAB9A (0.54) | RAB9ANPC1TDP1ALDH1A1HPGD | |
| SCHEMBL26634041 | 0.78 | ESR1 (0.63) | RAB9ANPC1TDP1ALDH1A1HPGD | |
| SCHEMBL31428564 | 0.78 | ESR1 (0.63) | RAB9ANPC1TDP1ALDH1A1HPGD | |
| SCHEMBL31428937 | 0.77 | HPGD (0.60) | RAB9ANPC1ALDH1A1HPGDKDM4E | |
| SCHEMBL30163508 | 0.77 | RAB9A (0.57) | RAB9ANPC1TDP1ALDH1A1HPGD | |
| SCHEMBL30163494 | 0.76 | RAB9A (0.54) | RAB9ANPC1TDP1ALDH1A1HPGD | |
| SCHEMBL30163490 | 0.74 | RAB9A (0.42) | RAB9ANPC1TDP1ALDH1A1HPGD | |
| SCHEMBL31428852 | 0.74 | RAB9A (0.42) | RAB9ANPC1TDP1ALDH1A1HPGD | |
| SCHEMBL24976103 | 0.72 | SMN1; SMN2 (0.52) | RAB9ANPC1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | RAB9A 67/4885NPC1 3237/4885TDP1 3630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.