Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30163490 | 1.00 | RAB9A (0.42) | RAB9AALDH1A1NPC1KDM4EPOLB | |
| SCHEMBL30163522 | 0.94 | RAB9A (0.42) | RAB9AALDH1A1NPC1KDM4EPOLB | |
| SCHEMBL30163476 | 0.85 | HPGD (0.45) | RAB9AALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL30163504 | 0.85 | HPGD (0.45) | RAB9AALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL31428618 | 0.82 | ALDH1A1 (0.45) | RAB9AALDH1A1NPC1KDM4EPOLB | |
| SCHEMBL30163519 | 0.80 | HPGD (0.46) | RAB9AALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL30163515 | 0.80 | HPGD (0.46) | RAB9AALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL31429114 | 0.79 | RAB9A (0.54) | RAB9AALDH1A1NPC1KDM4EPOLB | |
| SCHEMBL31428378 | 0.78 | MAPT (0.53) | RAB9AALDH1A1NPC1KDM4EPOLB | |
| SCHEMBL31428887 | 0.76 | PDCD1 (0.41) | ALDH1A1SMN1; SMN2MAPTHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | RAB9A 67/4885ALDH1A1 2352/4885NPC1 3237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.