Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428937 | 0.85 | HPGD (0.60) | SMN1; SMN2NPC1RAB9AHPGDLMNA | |
| SCHEMBL24975798 | 0.81 | ALDH1A1 (0.38) | SMN1; SMN2NPC1RAB9AHPGDHSD17B10 | |
| SCHEMBL10049918 | 0.74 | HPGD (0.75) | SMN1; SMN2HPGDHSD17B10LMNAALDH1A1 | |
| SCHEMBL31201758 | 0.74 | ALDH1A1 (0.56) | SMN1; SMN2NPC1RAB9AHPGDHSD17B10 | |
| SCHEMBL31428841 | 0.72 | RAB9A (0.55) | SMN1; SMN2NPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL470957 | 0.71 | HPGD (0.62) | SMN1; SMN2HPGDHSD17B10LMNAALDH1A1 | |
| SCHEMBL24975805 | 0.70 | LMNA (0.47) | SMN1; SMN2NPC1RAB9AHPGDHSD17B10 | |
| SCHEMBL1105986 | 0.70 | NPC1 (1.00) | SMN1; SMN2NPC1RAB9AHPGDHSD17B10 | |
| SCHEMBL14369308 | 0.69 | HPGD (0.53) | SMN1; SMN2NPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL20481983 | 0.68 | NPC1 (0.78) | SMN1; SMN2NPC1RAB9AHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |