Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.40 |
| ▸ | ITGAL | P20701 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 2/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428538 | 0.85 | HPGD (0.46) | ALDH1A1SMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL30163522 | 0.84 | RAB9A (0.42) | ALDH1A1SMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL31428852 | 0.82 | RAB9A (0.42) | ALDH1A1SMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL30163490 | 0.82 | RAB9A (0.42) | ALDH1A1SMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL31428590 | 0.81 | FKBP1A (0.41) | ALDH1A1SMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL31428480 | 0.81 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL31429006 | 0.80 | HPGD (0.47) | ALDH1A1SMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL30163475 | 0.78 | L3MBTL3 (0.42) | ALDH1A1SMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL31429062 | 0.77 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL31428532 | 0.76 | RAB9A (0.56) | ALDH1A1SMN1; SMN2MAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | ALDH1A1 2352/4885SMN1; SMN2 4832/4885MAPT 4513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.