Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31429006 | 0.84 | HPGD (0.47) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL31428538 | 0.83 | HPGD (0.46) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL31429038 | 0.82 | SMN1; SMN2 (0.45) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL31428704 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL31428847 | 0.79 | PLAUR (0.42) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL31428590 | 0.78 | FKBP1A (0.41) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL31428524 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL31428782 | 0.78 | PDCD1 (0.49) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL31428480 | 0.78 | ALDH1A1 (0.43) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL30163475 | 0.77 | L3MBTL3 (0.42) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | ALDH1A1 2352/4885HTT 4442/4885SMN1; SMN2 4832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.