SCHEMBL31429286

SCHEMBL31429286

c1ccc2c(c1)cnn2CC1CCNCC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.48
RECQL P46063 1/20 0.47
CYP1A2 P05177 1/20 0.44
CRHR1 P34998 1/20 0.43
KMO O15229 1/20 0.43
CHRM2 P08172 6/20 0.43
CHRM1 P11229 6/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CHRM3 P20309 1/20 0.42
MERTK Q12866 1/20 0.42
PRKD3 O94806 1/20 0.41
PRKD1 Q15139 1/20 0.41
PRKD2 Q9BZL6 1/20 0.41
HTR6 P50406 1/20 0.41
DDB1 Q16531 1/20 0.41
CRBN Q96SW2 1/20 0.41
TSHR P16473 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5946285 0.89 RECQL (0.54) ADRA2ARECQLCYP1A2CRHR1KMO
SCHEMBL31429406 0.86 RECQL (0.51) ADRA2ARECQLCYP1A2CRHR1KMO
SCHEMBL17845290 0.82 RECQL (0.47) ADRA2ARECQLCYP1A2CRHR1KMO
SCHEMBL29353804 0.77 CRHR1 (0.42) ADRA2ARECQLCYP1A2CRHR1KMO
SCHEMBL29353859 0.77 CRHR1 (0.42) ADRA2ARECQLCYP1A2CRHR1KMO
SCHEMBL31429403 0.77 RECQL (0.45) ADRA2ARECQLCYP1A2CRHR1KMO
SCHEMBL25741023 0.77 CHRM2 (0.49) ADRA2ARECQLCYP1A2CRHR1KMO
SCHEMBL9960182 0.75 CHRM2 (0.46) ADRA2ARECQLCYP1A2CRHR1KMO
SCHEMBL25740903 0.75 CHRM2 (0.48) ADRA2ARECQLCYP1A2CRHR1KMO
SCHEMBL25740899 0.75 CHRM2 (0.48) ADRA2ARECQLCYP1A2CRHR1KMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250092014-A1 COMPOUNDS AND METHODS OF ACTIVATING LIPOPROTEIN LIPASE METREA BIOSCIENCES INC (US) 2025-03-20 US claimed
US-20250092014-A1 COMPOUNDS AND METHODS OF ACTIVATING LIPOPROTEIN LIPASE METREA BIOSCIENCES INC (US) 2025-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250092014-A1 COMPOUNDS AND METHODS OF ACTIVATING LIPOPROTEIN LIPASE LPL, LIPA, PNLIP ADRA2A 1326/4885RECQL 1592/4885CYP1A2 973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.