Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31430361 | 0.91 | EPHX2 (0.48) | EPHX2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31430397 | 0.89 | EPHX2 (0.49) | EPHX2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31430174 | 0.81 | EPHX2 (0.38) | EPHX2MAPK14PDE4APDE4BPDE4C | |
| SCHEMBL31430329 | 0.74 | OTUD7B (0.40) | EPHX2 | |
| SCHEMBL31430243 | 0.74 | PRMT5 (0.42) | EPHX2MAPK14IP6K1IP6K3IP6K2 | |
| SCHEMBL5313889 | 0.73 | PGR (0.43) | MAPK14HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL25336042 | 0.72 | KMT2A (0.32) | KMT2A | |
| SCHEMBL31515307 | 0.72 | KMT2A (0.32) | KMT2A | |
| SCHEMBL31430254 | 0.72 | KMT2A (0.32) | KMT2A | |
| SCHEMBL31430234 | 0.72 | ADRA2B (0.50) | HTR1AHTR2AHTR7HTR6PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462695-A | Pyridine derivative and application thereof | 康百达（四川）生物医药科技有限公司 | 2025-02-18 | — | — | CN | disclosed |