Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.57 |
| ▸ | CTSB | P07858 | 2/20 | 0.57 |
| ▸ | DPP3 | Q9NY33 | 5/20 | 0.51 |
| ▸ | CXCL8 | P10145 | 6/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CTSH | P09668 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | MC5R | P33032 | 1/20 | 0.46 |
| ▸ | MC3R | P41968 | 1/20 | 0.46 |
| ▸ | MC1R | Q01726 | 1/20 | 0.46 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
| ▸ | APLNR | P35414 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433370 | 0.87 | CXCL8 (0.57) | CAPN1CTSBDPP3CXCL8 | |
| SCHEMBL31433384 | 0.87 | C5AR1 (0.56) | CXCL8CTSLCTSSCTSKMC4R | |
| SCHEMBL31247348 | 0.82 | CAPN1 (0.57) | CAPN1CTSBDPP3CXCL8CTSL | |
| SCHEMBL31247466 | 0.82 | CAPN1 (0.60) | CAPN1CTSBCXCL8CTSLCTSS | |
| SCHEMBL31247542 | 0.82 | CAPN1 (0.60) | CAPN1CTSBCXCL8CTSLCTSS | |
| SCHEMBL31247512 | 0.81 | CAPN1 (0.57) | CAPN1CTSBCXCL8CTSLCTSS | |
| SCHEMBL31433316 | 0.81 | CAPN1 (0.61) | CAPN1CTSBNTSR2NTSR1SORT1 | |
| SCHEMBL31249421 | 0.80 | CAPN1 (0.56) | CAPN1CTSBDPP3CXCL8MC4R | |
| SCHEMBL31357907 | 0.80 | CAPN1 (0.57) | CAPN1CTSBDPP3CXCL8NTSR2 | |
| SCHEMBL13697496 | 0.79 | CXCR4 (0.56) | CAPN1CTSBDPP3CXCL8NTSR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | CALICO LIFE SCIENCES LLC (US) | 2025-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | MICA, CD74, HLA-DRB1 | CAPN1 3160/4885CTSB 337/4885DPP3 882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.