SCHEMBL31433209

SCHEMBL31433209

NCCCC[C@H](NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC15A2 Q16348 1/20 0.45
ERAP2 Q6P179 4/20 0.39
LNPEP Q9UIQ6 4/20 0.39
TERT O14746 1/20 0.39
SLC6A5 Q9Y345 1/20 0.36
OPRD1 P41143 2/20 0.36
OPRM1 P35372 1/20 0.36
OPRK1 P41145 1/20 0.36
ERAP1 Q9NZ08 2/20 0.36
PRMT1 Q99873 1/20 0.36
FOLH1 Q04609 1/20 0.36
MMP2 P08253 1/20 0.35
C5AR1 P21730 1/20 0.35
ECE1 P42892 1/20 0.35
F2 P00734 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9747810 0.98 SLC15A2 (0.46) SLC15A2ERAP2LNPEPTERTSLC6A5
SCHEMBL8427583 0.98 SLC15A2 (0.46) SLC15A2ERAP2LNPEPTERTSLC6A5
SCHEMBL9748489 0.98 SLC15A2 (0.46) SLC15A2ERAP2LNPEPTERTSLC6A5
SCHEMBL31453807 0.94 SLC15A2 (0.50) SLC15A2ERAP2LNPEPTERTSLC6A5
SCHEMBL34464922 0.91 SLC15A2 (0.42) SLC15A2ERAP2LNPEPOPRD1OPRM1
SCHEMBL4958851 0.90 SLC15A2 (0.50) SLC15A2ERAP2LNPEPTERTOPRD1
SCHEMBL4958843 0.90 SLC15A2 (0.50) SLC15A2ERAP2LNPEPTERTOPRD1
SCHEMBL8832514 0.90 TERT (0.44) SLC15A2ERAP2LNPEPTERTOPRD1
SCHEMBL2823387 0.90 TERT (0.44) SLC15A2ERAP2LNPEPTERTOPRD1
SCHEMBL8832652 0.89 TERT (0.44) SLC15A2ERAP2LNPEPTERTOPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250074942-A1 COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E CALICO LIFE SCIENCES LLC (US) 2025-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250074942-A1 COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E MICA, CD74, HLA-DRB1 SLC15A2 1915/4885ERAP2 923/4885LNPEP 101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.