Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.50 |
| ▸ | IL23R | Q5VWK5 | 4/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.48 |
| ▸ | GLP1R | P43220 | 1/20 | 0.46 |
| ▸ | SCTR | P47872 | 1/20 | 0.46 |
| ▸ | NPY4R | P50391 | 3/20 | 0.45 |
| ▸ | NPY1R | P25929 | 2/20 | 0.45 |
| ▸ | NPY2R | P49146 | 2/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.45 |
| ▸ | TFPI | P10646 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433365 | 0.90 | TFPI (0.54) | IL23RNPBWR1NPY4RNPY1RNPY2R | |
| SCHEMBL31433357 | 0.90 | TFPI (0.54) | IL23RNPBWR1NPY4RNPY1RNPY2R | |
| SCHEMBL31433189 | 0.88 | IL23R (0.53) | IL23RNPBWR1NPY4RNPY1RNPY2R | |
| SCHEMBL30483663 | 0.87 | C5AR1 (0.54) | APLNRMC4RC5AR1GLP1RSCTR | |
| SCHEMBL31267994 | 0.87 | NPY4R (0.54) | APLNRNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30168744 | 0.86 | GLP1R (0.56) | MC4RGLP1RSCTR | |
| SCHEMBL30168729 | 0.86 | GLP1R (0.56) | MC4RGLP1RSCTR | |
| SCHEMBL29733646 | 0.86 | CALCR (0.49) | NPBWR1GLP1R | |
| SCHEMBL30264773 | 0.86 | APLNR (0.47) | APLNRNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL31433319 | 0.85 | IL23R (0.52) | IL23RNPBWR1NPY4RNPY1RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | CALICO LIFE SCIENCES LLC (US) | 2025-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | MICA, CD74, HLA-DRB1 | APLNR 2565/4885IL23R 710/4885MC4R 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.