Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI | P10646 | 1/20 | 0.54 |
| ▸ | IL23R | Q5VWK5 | 3/20 | 0.50 |
| ▸ | NPY4R | P50391 | 7/20 | 0.49 |
| ▸ | NPY1R | P25929 | 6/20 | 0.49 |
| ▸ | NPY2R | P49146 | 6/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.49 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433365 | 0.95 | TFPI (0.54) | TFPIIL23RNPY4RNPY1RNPY2R | |
| SCHEMBL31433189 | 0.93 | IL23R (0.53) | IL23RNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL29939684 | 0.91 | TFPI (0.57) | TFPIIL23RNPY4RNPY1RNPY2R | |
| SCHEMBL31433319 | 0.91 | IL23R (0.52) | TFPIIL23RNPY4RNPY1RNPY5R | |
| SCHEMBL31433367 | 0.90 | OPRM1 (0.49) | TFPIOPRL1NPBWR1OPRM1OPRD1 | |
| SCHEMBL31437674 | 0.90 | NPY4R (0.57) | TFPINPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL31433235 | 0.90 | APLNR (0.50) | TFPIIL23RNPY4RNPY1RNPY2R | |
| SCHEMBL29568797 | 0.89 | NPY4R (0.54) | TFPIIL23RNPY4RNPY1RNPY2R | |
| SCHEMBL31433226 | 0.88 | TFPI (0.48) | TFPIIL23R | |
| SCHEMBL31437671 | 0.88 | NPY4R (0.57) | TFPINPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | CALICO LIFE SCIENCES LLC (US) | 2025-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | MICA, CD74, HLA-DRB1 | TFPI 2582/4885IL23R 710/4885NPY4R 1616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.