Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.54 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.50 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.50 |
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6362025 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TSHRAOX1FDPSHPGD | |
| SCHEMBL23200984 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TSHRAOX1FDPSHPGD | |
| SCHEMBL2944791 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TSHRAOX1FDPSHPGD | |
| SCHEMBL2944789 | 0.81 | ALDH1A1 (0.62) | ALDH1A1TSHRAOX1FDPSHPGD | |
| SCHEMBL29786781 | 0.81 | ALDH1A1 (0.62) | ALDH1A1TSHRAOX1FDPSHPGD | |
| SCHEMBL3243188 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TSHRAOX1FDPSHPGD | |
| SCHEMBL17318087 | 0.78 | ALDH1A1 (0.68) | ALDH1A1TSHRAOX1FDPSHPGD | |
| SCHEMBL17318083 | 0.78 | ALDH1A1 (0.68) | ALDH1A1TSHRAOX1FDPSHPGD | |
| SCHEMBL9700245 | 0.77 | CYP2A6 (0.40) | ALDH1A1TSHRAOX1HPGDTRIM24 | |
| 3,4-Dimethoxybenzaldehyde SCHEMBL5308959 | 0.75 | ALDH1A1 (1.00) | ALDH1A1TSHRAOX1FDPSHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | CALICO LIFE SCIENCES LLC (US) | 2025-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | MICA, CD74, HLA-DRB1 | ALDH1A1 3213/4885TSHR 4329/4885AOX1 3085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.