SCHEMBL9700245

SCHEMBL9700245

Cc1ccc(C=O)cc1S(=O)(=O)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.40
ALDH1A1 P00352 10/20 0.39
ALDH1A3 P47895 2/20 0.39
TSHR P16473 1/20 0.37
POLB P06746 3/20 0.37
LMNA P02545 2/20 0.37
KDM4E B2RXH2 3/20 0.36
RAB9A P51151 2/20 0.36
PTGS2 P35354 1/20 0.36
HPGD P15428 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
AOX1 Q06278 1/20 0.34
TRIM24 O15164 1/20 0.34
ALDH5A1 P51649 1/20 0.34
ABAT P80404 1/20 0.34
TRIM33 Q9UPN9 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11575237 0.83 TDP1 (0.38) ALDH1A1POLBLMNAKDM4ERAB9A
SCHEMBL6432106 0.82 CYP2A6 (0.41) CYP2A6ALDH1A1ALDH1A3TSHRPOLB
SCHEMBL6433328 0.81 POLB (0.41) CYP2A6ALDH1A1ALDH1A3TSHRPOLB
SCHEMBL18231235 0.81 CA1 (0.43) CYP2A6ALDH1A1ALDH1A3KDM4ERAB9A
SCHEMBL9067089 0.79 LMNA (0.46) CYP2A6ALDH1A1ALDH1A3TSHRPOLB
SCHEMBL31433420 0.77 ALDH1A1 (0.59) ALDH1A1ALDH1A3TSHRPOLBLMNA
SCHEMBL9617406 0.74 LMNA (0.50) ALDH1A1TSHRPOLBLMNAHPGD
SCHEMBL9700422 0.72 GRIA1 (0.41) ALDH1A1TSHRKDM4ERAB9APTGS2
SCHEMBL29452128 0.72 L3MBTL1 (0.52) ALDH1A1TSHRPOLBLMNAKDM4E
SCHEMBL98097 0.72 CYP2A6 (0.52) CYP2A6ALDH1A1ALDH1A3TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3255062-A None JP disclosed
US-5095150-A FORMYLATED ALKLBENZENESULFONYL HALIDE COMPOUND AND PROCESS FOR PREPARING THE SAME AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) 1992-03-10 US disclosed
JP-H03255062-A FORMYLALKYLBENZENESULFONYL FLUORIDE AND ITS PRODUCTION AGENCY OF IND SCIENCE & TECHNOL 1991-11-13 JP disclosed
US-5030752-A Formylated alkylbenzenesulfonyl halide compound AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1991-07-09 US disclosed