Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 9/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.34 |
| ▸ | CDK9 | P50750 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433828 | 1.00 | GPR119 (0.36) | GPR119DGAT2PRMT5WDR77BTK | |
| SCHEMBL30731912 | 0.94 | GPR119 (0.37) | GPR119DGAT2PRMT5WDR77BTK | |
| SCHEMBL30731817 | 0.94 | GPR119 (0.37) | GPR119DGAT2PRMT5WDR77BTK | |
| SCHEMBL30732188 | 0.94 | GPR119 (0.37) | GPR119DGAT2PRMT5WDR77BTK | |
| SCHEMBL31433618 | 0.91 | TNF (0.37) | GPR119DGAT2PRMT5BTKCCNT1 | |
| SCHEMBL31433651 | 0.91 | TNF (0.37) | GPR119DGAT2PRMT5BTKCCNT1 | |
| SCHEMBL30732266 | 0.90 | PRMT5 (0.38) | GPR119PRMT5WDR77BRD4HTR6 | |
| SCHEMBL26925378 | 0.90 | PRMT5 (0.38) | GPR119PRMT5WDR77BRD4HTR6 | |
| SCHEMBL31433862 | 0.89 | CCNT1 (0.34) | GPR119DGAT2PRMT5BTKCCNT1 | |
| SCHEMBL31433844 | 0.89 | CCNT1 (0.34) | GPR119DGAT2PRMT5BTKCCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |