Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 9/20 | 0.43 |
| ▸ | GRM5 | P41594 | 8/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | EED | O75530 | 4/20 | 0.42 |
| ▸ | RBBP4 | Q09028 | 4/20 | 0.42 |
| ▸ | SUZ12 | Q15022 | 4/20 | 0.42 |
| ▸ | EZH2 | Q15910 | 4/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433997 | 0.84 | TNF (0.44) | GRM1GRM5PDK4EEDRBBP4 | |
| SCHEMBL31433780 | 0.83 | GRM1 (0.45) | GRM1GRM5PDK4EEDRBBP4 | |
| SCHEMBL21797028 | 0.81 | PDK4 (0.41) | GRM1GRM5PDK4EEDRBBP4 | |
| SCHEMBL30447330 | 0.79 | GPR119 (0.40) | GRM1GRM5PDK4EEDRBBP4 | |
| SCHEMBL31434059 | 0.79 | ALOX5AP (0.44) | GPR119 | |
| SCHEMBL34468854 | 0.77 | GRM1 (0.46) | GRM1GRM5PDK4EEDRBBP4 | |
| SCHEMBL31433915 | 0.74 | TNF (0.45) | GRM1GRM5PDK4EEDRBBP4 | |
| SCHEMBL25305978 | 0.74 | GRM1 (0.47) | GRM1GRM5PDK4ATRGPR119 | |
| SCHEMBL29900848 | 0.73 | GRM5 (0.41) | GRM1GRM5EEDRBBP4SUZ12 | |
| SCHEMBL31088401 | 0.73 | PDK4 (0.35) | GRM1GRM5PDK4EEDRBBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |