Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 6/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | EED | O75530 | 4/20 | 0.39 |
| ▸ | RBBP4 | Q09028 | 4/20 | 0.39 |
| ▸ | SUZ12 | Q15022 | 4/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 4/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21797028 | 0.91 | PDK4 (0.41) | GRM5GRM1PDK4TLR7JAK1 | |
| SCHEMBL31433719 | 0.84 | GRM1 (0.43) | GRM5GRM1PDK4JAK1GPR119 | |
| SCHEMBL31433915 | 0.83 | TNF (0.45) | TNFGRM5GRM1PDK4TLR7 | |
| SCHEMBL31281722 | 0.81 | PDK4 (0.41) | TNFGRM5GRM1PDK4TLR7 | |
| SCHEMBL31282008 | 0.81 | PDK4 (0.41) | TNFGRM5GRM1PDK4TLR7 | |
| SCHEMBL30447330 | 0.81 | GPR119 (0.40) | GRM5GRM1PDK4JAK1GPR119 | |
| SCHEMBL21796921 | 0.79 | JAK2 (0.31) | JAK1 | |
| SCHEMBL31433802 | 0.79 | GPR119 (0.41) | GPR119 | |
| SCHEMBL22873680 | 0.78 | TNF (0.48) | TNFGRM5GRM1PDK4JAK1 | |
| SCHEMBL34468854 | 0.77 | GRM1 (0.46) | GRM5GRM1PDK4JAK1EED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |