Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 11/20 | 0.45 |
| ▸ | GRM5 | P41594 | 10/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | EED | O75530 | 3/20 | 0.39 |
| ▸ | RBBP4 | Q09028 | 3/20 | 0.39 |
| ▸ | SUZ12 | Q15022 | 3/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34468854 | 0.85 | GRM1 (0.46) | GRM1GRM5PDK4HTR6JAK1 | |
| SCHEMBL31433915 | 0.83 | TNF (0.45) | GRM1GRM5PDK4HTR6JAK1 | |
| SCHEMBL31433719 | 0.83 | GRM1 (0.43) | GRM1GRM5PDK4JAK1EED | |
| SCHEMBL25305978 | 0.82 | GRM1 (0.47) | GRM1GRM5PDK4HTR6ENPP2 | |
| SCHEMBL31434010 | 0.79 | CNR1 (0.42) | NAMPTGPR119 | |
| SCHEMBL29319317 | 0.75 | KIT (0.44) | GRM1GRM5PDK4HTR6EED | |
| SCHEMBL31433997 | 0.74 | TNF (0.44) | GRM1GRM5PDK4HTR6JAK1 | |
| SCHEMBL31164588 | 0.74 | GRM1 (0.40) | GRM1GRM5PDK4HTR6JAK1 | |
| SCHEMBL12874666 | 0.74 | GRM1 (0.49) | GRM1GRM5PDK4HTR6EED | |
| SCHEMBL29907270 | 0.74 | PDK4 (0.49) | GRM1GRM5PDK4HTR6EED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |