Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.45 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.45 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4511114 | 0.87 | ROCK2 (0.56) | ROCK2CISD1CA12CA1CA2 | |
| SCHEMBL4514005 | 0.81 | CA1 (0.51) | ROCK2CISD1CA12CA1CA2 | |
| SCHEMBL3313227 | 0.81 | CA1 (0.53) | ROCK2CISD1CA12CA1CA2 | |
| SCHEMBL15635143 | 0.81 | CA1 (0.50) | ROCK2CISD1CA12CA1CA2 | |
| SCHEMBL6801259 | 0.78 | CA1 (0.54) | ROCK2CISD1CA12CA1CA2 | |
| SCHEMBL25335478 | 0.77 | ROCK2 (0.42) | ROCK2PIM1GAAKDM4E | |
| SCHEMBL16004173 | 0.77 | KCNK2 (0.49) | KCNK2KCNK10CA12CA1CA2 | |
| SCHEMBL21384569 | 0.77 | ACLY (0.48) | KCNK2KCNK10KDM4ETDP1 | |
| SCHEMBL28974855 | 0.76 | ROCK2 (0.42) | ROCK2KMT2APIM1PIM2NPC1 | |
| Hydrochloric Acid SCHEMBL21988903 | 0.76 | KCNK2 (0.48) | KCNK2KCNK10CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |