Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434059 | 0.83 | ALOX5AP (0.44) | GPR119CNR1CNR2 | |
| SCHEMBL31433908 | 0.82 | GPR119 (0.41) | GPR119SMN1; SMN2TRPV3CNR1CNR2 | |
| SCHEMBL18398964 | 0.81 | LRRK2 (0.38) | GPR119MAPT | |
| SCHEMBL21796987 | 0.81 | LRRK2 (0.38) | GPR119MAPT | |
| SCHEMBL21796989 | 0.81 | LRRK2 (0.38) | GPR119MAPT | |
| SCHEMBL21797124 | 0.80 | GPR119 (0.37) | GPR119MAPT | |
| SCHEMBL21797125 | 0.80 | GPR119 (0.37) | GPR119MAPT | |
| SCHEMBL18399001 | 0.80 | GPR119 (0.37) | GPR119MAPT | |
| SCHEMBL31433997 | 0.79 | TNF (0.44) | GPR119 | |
| SCHEMBL18399269 | 0.77 | LRRK2 (0.45) | GPR119SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |