Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20440617 | 0.90 | HPGD (0.41) | GPR119ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL31434010 | 0.82 | CNR1 (0.42) | GPR119TRPV3ALDH1A1HPGDKDM4E | |
| SCHEMBL25306093 | 0.82 | MAPT (0.42) | GPR119TRPV3ALDH1A1HPGDKDM4E | |
| SCHEMBL31433802 | 0.82 | GPR119 (0.41) | GPR119TRPV3MAPTCNR1CNR2 | |
| SCHEMBL29319329 | 0.81 | KDM4E (0.40) | GPR119ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL31433915 | 0.79 | TNF (0.45) | GPR119 | |
| SCHEMBL30926359 | 0.78 | SMN1; SMN2 (0.43) | GPR119TRPV3ALDH1A1HPGDKDM4E | |
| SCHEMBL25213813 | 0.75 | GPR119 (0.38) | GPR119ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL25308464 | 0.75 | ALOX5AP (0.35) | GPR119TRPV3KDM4EMAPTNAMPT | |
| SCHEMBL31434059 | 0.73 | ALOX5AP (0.44) | GPR119HPGDMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |