SCHEMBL3143381

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Bromide SCHEMBL3147500	0.85	MCHR1 (0.38)	CMA1ALDH1A1HTTL3MBTL1LMNA
	SCHEMBL3143373	0.85	LMNA (0.37)	CMA1ALDH1A1HTTL3MBTL1LMNA
	SCHEMBL3138421	0.85	MCHR1 (0.38)	CMA1ALDH1A1HTTL3MBTL1LMNA
	Bromide SCHEMBL3142390	0.82	MCHR1 (0.37)	ALDH1A1LMNAGAA
	SCHEMBL3138736	0.71	MCHR1 (0.39)	LMNATAS2R8
	Bromide SCHEMBL3147496	0.71	LMNA (0.39)	ALDH1A1HTTL3MBTL1LMNATAS2R8
	SCHEMBL3138416	0.70	LMNA (0.38)	ALDH1A1HTTL3MBTL1LMNATAS2R8
	SCHEMBL3138424	0.70	LMNA (0.38)	ALDH1A1HTTL3MBTL1LMNATAS2R8
	SCHEMBL3128722	0.69	KDM4E (0.49)	ALDH1A1HTTLMNAKMT2AMEN1
	SCHEMBL3134678	0.68	HDAC1 (0.46)	L3MBTL1LMNAMAPTGAANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.