Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.35 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | FER | P16591 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3150964 | 0.85 | LMNA (0.35) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL15763606 | 0.85 | LMNA (0.39) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL3947944 | 0.79 | CSNK2A2 (0.39) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL6823069 | 0.77 | PDE4B (0.41) | ALDH1A1KDM4ECDK2LMNATP53 | |
| SCHEMBL26513225 | 0.76 | MEN1 (0.40) | RXFP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1009822 | 0.75 | SLC2A1 (0.39) | ALDH1A1MAPTGAACSNK2A1LMNA | |
| SCHEMBL9898544 | 0.74 | KCNA5 (0.41) | ALDH1A1MEN1KMT2ADPP4MAPT | |
| SCHEMBL824275 | 0.72 | ALDH1A1 (0.48) | PRNPPPARGRXFP1NR2E3NCOR2 | |
| SCHEMBL4584724 | 0.72 | ALDH1A1 (0.48) | PRNPPPARGRXFP1NR2E3NCOR2 | |
| SCHEMBL4649729 | 0.71 | DPP4 (0.40) | PRNPPPARGRXFP1NR2E3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963896-B1 | PHOTOCHROMIC MATERIALS HAVING ELECTRON-WITHDRAWING SUBSTITUENTS | TRANSITIONS OPTICAL INC (US) | 2010-02-10 | — | — | EP | disclosed |
| US-7556751-B2 | Photochromic materials having electron-withdrawing substituents | TRANSITIONS OPTICAL, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-20070138449-A1 | Photochromic materials having electron-withdrawing substituents | TRANSITIONS OPTICAL LIMITED (IE) | 2007-06-21 | — | — | US | disclosed |