Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433970 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL31433864 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL19086540 | 0.81 | HIF1A (0.45) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5529472 | 0.81 | ALDH1A1 (0.69) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL31329665 | 0.81 | ALDH1A1 (0.69) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL15966805 | 0.81 | ALDH1A1 (0.77) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL11375460 | 0.79 | ALDH1A1 (0.63) | ALDH1A1KDM4ESMN1; SMN2KMT2ALMNA | |
| SCHEMBL31433759 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL5525935 | 0.78 | ALDH1A1 (0.72) | ALDH1A1KDM4ESMN1; SMN2GAAKMT2A | |
| SCHEMBL15154629 | 0.77 | ALDH1A1 (0.70) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |