Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11377362 | 0.86 | ALDH1A1 (0.67) | ALDH1A1KDM4ESMN1; SMN2LMNAKMT2A | |
| SCHEMBL11638740 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KDM4ESMN1; SMN2LMNAKMT2A | |
| SCHEMBL11818406 | 0.84 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2LMNAKMT2A | |
| SCHEMBL11383580 | 0.82 | ALDH1A1 (0.67) | ALDH1A1KDM4ESMN1; SMN2LMNAKMT2A | |
| SCHEMBL11373100 | 0.82 | MEN1 (0.50) | ALDH1A1KDM4EKMT2AMEN1TSHR | |
| SCHEMBL11383233 | 0.82 | LMNA (0.53) | ALDH1A1KDM4ESMN1; SMN2LMNAKMT2A | |
| SCHEMBL11388773 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2LMNAKMT2A | |
| SCHEMBL8784910 | 0.81 | TSHR (0.56) | ALDH1A1KDM4ESMN1; SMN2LMNAKMT2A | |
| SCHEMBL11377101 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2LMNARECQL | |
| SCHEMBL11393959 | 0.81 | LMNA (0.67) | ALDH1A1KDM4ESMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273930-A | INTERMEDIATES FOR THE 4-ALKOXY ANTIALLERGENS | SANDOZ, INC. (US) | 1981-06-16 | — | — | US | claimed |
| US-4190659-A | ANTIALLERGENS, ANTIHISTAMINES | SANDOZ, INC. (US) | 1980-02-26 | — | — | US | claimed |
| US-4281131-A | ANTIALLERGENS | SANDOZ, INC. (US) | 1981-07-28 | — | — | US | disclosed |
| US-4273930-A | INTERMEDIATES FOR THE 4-ALKOXY ANTIALLERGENS | SANDOZ, INC. (US) | 1981-06-16 | — | — | US | disclosed |
| US-4190659-A | ANTIALLERGENS, ANTIHISTAMINES | SANDOZ, INC. (US) | 1980-02-26 | — | — | US | disclosed |
| US-4187309-A | ANTIALLERGENS, ANTIHISTAMINES | SANDOZ, INC. (US) | 1980-02-05 | — | — | US | disclosed |