SCHEMBL3143397

SCHEMBL3143397

Nc1ccc(Oc2ccc(C(F)C(F)(F)C(F)(F)F)cc2)c(C(F)(F)F)c1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
GLA P06280 1/20 0.39
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.36
RAB9A P51151 1/20 0.36
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
ATM Q13315 1/20 0.34
FFAR1 O14842 3/20 0.33
SCN9A Q15858 8/20 0.32
LTA4H P09960 1/20 0.32
PTGS2 P35354 1/20 0.32
NR1H2 P55055 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PLA2G7 Q13093 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27940216 0.86 L3MBTL1 (0.43) TSHRPOLBGAAL3MBTL1RAB9A
SCHEMBL649657 0.84 TSHR (0.53) TSHRGLAPOLBGAAL3MBTL1
SCHEMBL29352455 0.84 TSHR (0.53) TSHRGLAPOLBGAAL3MBTL1
SCHEMBL28390796 0.84 PDE7A (0.43) TSHRL3MBTL1RAB9AMAPTFFAR1
SCHEMBL1352801 0.82 TSHR (0.52) TSHRGLAPOLBGAAL3MBTL1
SCHEMBL29448858 0.82 TSHR (0.52) TSHRGLAPOLBGAAL3MBTL1
SCHEMBL7187793 0.82 TSHR (0.52) TSHRGLAPOLBGAAL3MBTL1
SCHEMBL31317722 0.82 TSHR (0.42) TSHRGLAPOLBGAAL3MBTL1
SCHEMBL28080262 0.82 TSHR (0.42) TSHRGLAPOLBGAAL3MBTL1
SCHEMBL28554615 0.81 NCOA1 (0.39) TSHRGLAPOLBGAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114605776-A Modified epoxy resin and preparation method thereof 中国航空制造技术研究院 2022-06-10 CN claimed
CN-111708252-A Photosensitive frame covering film for flexible folding screen 浙江福斯特新材料研究院有限公司 2020-09-25 CN claimed
CN-109852340-A A kind of YASI-BDAPOFP type Organic fluoride silica gel and preparation method thereof 福建省海钛智能科技有限公司 2019-06-07 CN claimed
CN-109735293-A A kind of DAB biphenyl tetramine type silicon-containing adhesive and preparation method thereof 东华大学 2019-05-10 CN claimed
CN-109722209-A A kind of YASI organic imides silica gel and preparation method thereof 东华大学 2019-05-07 CN claimed
US-5756649-A HAVING THE ABILITY TO CHANGE THE PRETILT ANGLE WITH RADIATION JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-05-26 US claimed
CN-110324974-B Metal-clad laminate and circuit board 日铁化学材料株式会社 2024-07-02 CN disclosed
CN-117050306-A Method for producing polyimide 日铁化学材料株式会社 2023-11-14 CN disclosed
CN-113874420-B Resin film and metal-clad laminate 日铁化学材料株式会社 2023-09-26 CN disclosed
CN-116478399-A Film, multilayer electronic device, and method for producing film 爱思开迈克沃有限公司 2023-07-25 CN disclosed
CN-116367413-A Metal-clad laminate and circuit board 日铁化学材料株式会社 2023-06-30 CN disclosed
CN-116353168-A Resin laminate, circuit board, electronic component, and electronic device 日铁化学材料株式会社 2023-06-30 CN disclosed
CN-115703283-A Film, light-transmitting laminate, cover film, and multilayer electronic device SKC株式会社 2023-02-17 CN disclosed
EP-1782881-B1 Membrane and associated method GEN ELECTRIC (US) 2010-02-10 EP disclosed
EP-1783147-B1 Composition and associated method GEN ELECTRIC (US) 2009-05-13 EP disclosed
EP-1783147-A1 Composition and associated method GENERAL ELECTRIC COMPANY (US) 2007-05-09 EP disclosed
EP-1782881-A1 Membrane and associated method General Electric Company (US) 2007-05-09 EP disclosed
US-5773559-A POLYAMIC ACID, POLYIMIDE BLOCK POLYMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-06-30 US disclosed
US-5756649-A HAVING THE ABILITY TO CHANGE THE PRETILT ANGLE WITH RADIATION JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-05-26 US disclosed
US-5700860-A Liquid crystal orienting agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-12-23 US disclosed