SCHEMBL28080262

SCHEMBL28080262

CC(C)c1ccc(Oc2ccc(N)cc2C(F)(F)F)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
POLB P06746 2/20 0.42
GLA P06280 1/20 0.42
GAA P10253 1/20 0.42
L3MBTL1 Q9Y468 3/20 0.41
RAB9A P51151 3/20 0.41
FFAR1 O14842 2/20 0.39
MAPT P10636 3/20 0.39
LMNA P02545 1/20 0.39
ATM Q13315 1/20 0.39
AR P10275 2/20 0.38
ALDH1A1 P00352 4/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ICAM1 P05362 1/20 0.38
SELE P16581 1/20 0.38
CYP3A4 P08684 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PDE7A Q13946 2/20 0.37
NPC1 O15118 2/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1352801 0.89 TSHR (0.52) TSHRPOLBGLAGAAL3MBTL1
SCHEMBL29448858 0.89 TSHR (0.52) TSHRPOLBGLAGAAL3MBTL1
SCHEMBL29352455 0.87 TSHR (0.53) TSHRPOLBGLAGAAL3MBTL1
SCHEMBL649657 0.87 TSHR (0.53) TSHRPOLBGLAGAAL3MBTL1
SCHEMBL17718747 0.86 AR (0.42) L3MBTL1RAB9AFFAR1MAPTLMNA
SCHEMBL7187793 0.86 TSHR (0.52) TSHRPOLBGLAGAAL3MBTL1
SCHEMBL31317722 0.85 TSHR (0.42) TSHRPOLBGLAGAAL3MBTL1
SCHEMBL27952327 0.85 L3MBTL1 (0.42) TSHRPOLBGLAGAAL3MBTL1
SCHEMBL5583700 0.83 TEAD4 (0.52) TSHRPOLBGLAGAAL3MBTL1
SCHEMBL1773615 0.83 MAOA (0.52) TSHRPOLBGLAGAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104760369-B A kind of fluorinated polyimide copper coated foil plate and preparation method thereof 东华大学 2016-08-24 CN disclosed