Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 5/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.41 |
| ▸ | GABRP | O00591 | 3/20 | 0.41 |
| ▸ | GABRD | O14764 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.41 |
| ▸ | GABRE | P78334 | 3/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434701 | 0.87 | NR1H4 (0.39) | OXTRAVPR2AVPR1AAVPR1B | |
| SCHEMBL31434641 | 0.87 | GABRA2 (0.40) | GABRA2GABRB2GABRG2GABRB3GABRA5 | |
| SCHEMBL31434600 | 0.86 | CYP1A2 (0.40) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL31434754 | 0.84 | GABRA2 (0.45) | GABRA2GABRB2GABRG2GABRB3GABRA5 | |
| SCHEMBL31434586 | 0.83 | CYP1A2 (0.36) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL31434635 | 0.82 | CYP1A2 (0.36) | CYP1A2MAPTSMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL31434616 | 0.82 | CDC7 (0.36) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL31434740 | 0.82 | CYP1A2 (0.36) | GABRA2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL31434593 | 0.81 | SYK (0.36) | CYP1A2L3MBTL1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL31434804 | 0.79 | CYP1A2 (0.39) | GABRA2GABRB2GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085347-A1 | IL4I1 INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-04-24 | — | — | WO | disclosed |