Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434641 | 0.90 | GABRA2 (0.40) | GABRA2GABRB2TRPM8ALDH1A1KDM4E | |
| SCHEMBL31434740 | 0.85 | CYP1A2 (0.36) | GABRA2MMP13CYP1A2GABRG2GABRB3 | |
| SCHEMBL31434600 | 0.85 | CYP1A2 (0.40) | GABRA2GABRB2ALDH1A1KDM4EHPGD | |
| SCHEMBL31434850 | 0.84 | LIPG (0.39) | MMP1MMP13KDM4EGAAKMT2A | |
| SCHEMBL31434723 | 0.84 | GABRA2 (0.44) | GABRA2GABRB2TRPM8MMP1MMP13 | |
| SCHEMBL31434705 | 0.84 | GABRA2 (0.41) | GABRA2GABRB2ALDH1A1KDM4ENPC1 | |
| SCHEMBL31434586 | 0.84 | CYP1A2 (0.36) | GABRA2GABRB2NPC1MEN1KMT2A | |
| SCHEMBL31434635 | 0.83 | CYP1A2 (0.36) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31434616 | 0.83 | CDC7 (0.36) | GABRA2GABRB2NPC1RAB9AHSD17B10 | |
| SCHEMBL31434593 | 0.82 | SYK (0.36) | ALDH1A1NPC1RAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085347-A1 | IL4I1 INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-04-24 | — | — | WO | disclosed |