Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TARBP2 | Q15633 | 6/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434600 | 0.85 | CYP1A2 (0.40) | CYP1A2TARBP2PDGFRBPDGFRANPC1 | |
| SCHEMBL31434709 | 0.85 | HPGDS (0.38) | LTA4H | |
| SCHEMBL31434754 | 0.83 | GABRA2 (0.45) | CYP1A2NPC1RAB9AHSD17B10GABRA2 | |
| SCHEMBL31434586 | 0.82 | CYP1A2 (0.36) | CYP1A2TARBP2NLRP3PDGFRBPDGFRA | |
| SCHEMBL31434705 | 0.82 | GABRA2 (0.41) | CYP1A2TARBP2NLRP3NPC1LMNA | |
| SCHEMBL31434740 | 0.81 | CYP1A2 (0.36) | CYP1A2NLRP3PDGFRBPDGFRAGABRA2 | |
| SCHEMBL31434635 | 0.81 | CYP1A2 (0.36) | CDC7DBF4CYP1A2NLRP3PDGFRB | |
| SCHEMBL31434593 | 0.80 | SYK (0.36) | CDC7DBF4CYP1A2NLRP3NPC1 | |
| SCHEMBL31434641 | 0.80 | GABRA2 (0.40) | CDC7DBF4NLRP3NPC1RAB9A | |
| SCHEMBL31434804 | 0.78 | CYP1A2 (0.39) | CYP1A2NLRP3NPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085347-A1 | IL4I1 INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-04-24 | — | — | WO | disclosed |