Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.42 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434772 | 0.89 | PPARA (0.47) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL31434818 | 0.88 | CDC7 (0.44) | CDC7DBF4MMP2MMP13MMP14 | |
| SCHEMBL31434778 | 0.86 | SCD (0.46) | RAB9ANPC1POLBKMT2AMAPT | |
| SCHEMBL31434631 | 0.83 | CYP2C9 (0.47) | CDC7DBF4MMP2MMP13MMP14 | |
| SCHEMBL31434844 | 0.83 | TP53 (0.48) | RAB9ANPC1KDM4EPOLBKMT2A | |
| SCHEMBL7424477 | 0.82 | L3MBTL1 (0.52) | CDC7DBF4MMP2MMP13MMP14 | |
| SCHEMBL30046162 | 0.82 | L3MBTL1 (0.52) | CDC7DBF4MMP2MMP13MMP14 | |
| SCHEMBL31434685 | 0.81 | MAPT (0.48) | RAB9ANPC1KDM4EPOLBKMT2A | |
| SCHEMBL12571350 | 0.76 | CDC7 (0.49) | CDC7DBF4MMP2MMP13MMP14 | |
| SCHEMBL31434796 | 0.74 | ALDH1A1 (0.56) | RAB9ANPC1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085347-A1 | IL4I1 INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-04-24 | — | — | WO | disclosed |