Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ACR | P10323 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434772 | 0.89 | PPARA (0.47) | TP53MAPTGABRA2GABRB2NPC1 | |
| SCHEMBL31434818 | 0.88 | CDC7 (0.44) | MAPTACRPOLB | |
| SCHEMBL31434703 | 0.85 | RAB9A (0.45) | TP53MAPTMEN1KMT2ANPC1 | |
| SCHEMBL31434741 | 0.83 | CDC7 (0.42) | TP53MAPTMEN1KMT2ANPC1 | |
| SCHEMBL31434754 | 0.81 | GABRA2 (0.45) | MAPTMEN1KMT2AGABRA2GABRB2 | |
| SCHEMBL1686391 | 0.81 | TP53 (0.62) | TP53MAPTMEN1KMT2AGABRA2 | |
| SCHEMBL31434723 | 0.80 | GABRA2 (0.44) | TP53MAPTGABRA2GABRB2NPC1 | |
| SCHEMBL754523 | 0.80 | ALDH1A1 (0.46) | MAPTMEN1KMT2AGABRA2GABRB2 | |
| SCHEMBL31434685 | 0.80 | MAPT (0.48) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL31434641 | 0.78 | GABRA2 (0.40) | MEN1KMT2AGABRA2GABRB2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085347-A1 | IL4I1 INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-04-24 | — | — | WO | disclosed |