Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20247288 | 0.86 | ATM (0.43) | ATMTDP1TDO2MEN1RAB9A | |
| SCHEMBL18531440 | 0.84 | TDO2 (0.42) | ATMTDP1TDO2MEN1RAB9A | |
| SCHEMBL9848594 | 0.83 | MEN1 (0.56) | ATMTDP1MEN1RAB9AKMT2A | |
| SCHEMBL23535461 | 0.81 | TDO2 (0.41) | ATMTDP1TDO2MEN1RAB9A | |
| SCHEMBL15577394 | 0.80 | CYP1A2 (0.53) | ATMTDP1TDO2MEN1RAB9A | |
| SCHEMBL29706788 | 0.80 | CYP1A2 (0.53) | ATMTDP1TDO2MEN1RAB9A | |
| SCHEMBL12984012 | 0.79 | PDK1 (0.41) | TDP1MAPK1PDK1ALDH1A1POLB | |
| SCHEMBL30886409 | 0.79 | TDO2 (0.39) | ATMTDP1TDO2MEN1RAB9A | |
| SCHEMBL7335 | 0.79 | ATM (0.55) | ATMTDP1TDO2MEN1RAB9A | |
| SCHEMBL29663529 | 0.79 | ATM (0.55) | ATMTDP1TDO2MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025044897-A1 | CYCLIC 2-AMINOPYRIMIDINE COMPOUND AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 中国科学院上海有机化学研究所 | 2025-03-06 | — | — | WO | disclosed |