Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25412105 | 1.00 | CYP2C19 (0.48) | CYP2C19POLBMEN1KMT2ARAB9A | |
| SCHEMBL25410988 | 0.82 | CRHBP (0.47) | CYP2C19POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL7647604 | 0.81 | MEN1 (0.67) | CYP2C19POLBMEN1KMT2ARAB9A | |
| SCHEMBL31381443 | 0.81 | MEN1 (0.67) | CYP2C19POLBMEN1KMT2ARAB9A | |
| SCHEMBL2950974 | 0.79 | CRHBP (0.50) | POLBMEN1KMT2AALDH1A1CRHBP | |
| SCHEMBL31435477 | 0.79 | CYP2C19 (0.45) | CYP2C19POLBMEN1KMT2ARAB9A | |
| SCHEMBL25409660 | 0.79 | CYP2C19 (0.45) | CYP2C19POLBMEN1KMT2ARAB9A | |
| SCHEMBL25410362 | 0.77 | HDAC1 (0.50) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6691391 | 0.75 | APP (0.48) | MEN1KMT2AALDH1A1CRHBPCRHR2 | |
| SCHEMBL6689802 | 0.73 | CRHBP (0.47) | POLBMEN1KMT2AALDH1A1CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301127-A | 6-Oxo-decahydro pyrrolo [1,2-a ] [1,5] diazocine and 6-oxo-decahydro-4H-pyrrolo [2,1-d ] [1,5] thiaazacine derivatives as modulators of STAT3 and STAT6 for the treatment of cancer and inflammatory conditions | 瑞克鲁迪克斯制药股份有限公司 | 2025-01-10 | — | — | CN | disclosed |