Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259352 | 0.81 | ALDH1A1 (0.63) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL2950974 | 0.80 | CRHBP (0.50) | CRHBPCRHR2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL28192852 | 0.78 | BACE1 (0.45) | ALDH1A1CHEK1TSHR | |
| SCHEMBL25410988 | 0.77 | CRHBP (0.47) | CRHBPCRHR2ALDH1A1TDP1ABCC1 | |
| SCHEMBL7564163 | 0.76 | ALDH1A1 (0.61) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL6691391 | 0.75 | APP (0.48) | CRHBPCRHR2ALDH1A1TDP1ABCC1 | |
| SCHEMBL23529914 | 0.75 | CRHBP (0.57) | CRHBPCRHR2ALDH1A1TDP1TSHR | |
| SCHEMBL8576604 | 0.74 | ALDH1A1 (0.59) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL17742439 | 0.74 | TDP1 (0.66) | CRHBPCRHR2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL1663325 | 0.73 | CRHBP (0.63) | CRHBPCRHR2CYP11B1CYP11B2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074300-A2 | NOVEL PHOTOLABILE PROTECTIVE GROUPS FOR IMPROVED PROCESSES TO PREPARE OLIGONUCLEOTIDE ARRAYS | NIGU CHEMIE GMBH (DE) | 2004-09-02 | — | — | WO | disclosed |