Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TLR2 | O60603 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31435597 | 0.87 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAKMT2AKDM4E | |
| SCHEMBL9722751 | 0.72 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2LMNAKMT2AKDM4E | |
| SCHEMBL31435555 | 0.72 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNAKDM4EHPGD | |
| SCHEMBL31435578 | 0.69 | DRD4 (0.44) | ALDH1A1KDM4EPOLB | |
| SCHEMBL31435611 | 0.69 | HDAC6 (0.39) | ALDH1A1LMNA | |
| SCHEMBL31435609 | 0.66 | CYP11B2 (0.37) | ALDH1A1LMNA | |
| SCHEMBL3318720 | 0.66 | PTGS2 (0.70) | ALDH1A1SMN1; SMN2KDM4EHPGDUSP2 | |
| SCHEMBL25299953 | 0.65 | ERN1 (0.45) | ALDH1A1SMN1; SMN2LMNAHPGDMAPT | |
| SCHEMBL21597638 | 0.65 | KDM4E (0.67) | ALDH1A1SMN1; SMN2LMNARAB9AKDM4E | |
| SCHEMBL22102931 | 0.64 | ACACB (0.39) | ALDH1A1LMNARAB9AKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661516-A | Bicyclic heterocyclic compounds, preparation method and medical application thereof | 华润医药研究院（深圳）有限公司 | 2025-03-21 | — | — | CN | disclosed |