SCHEMBL3143580

SCHEMBL3143580

Cc1ccc(S(=O)(=O)OS(c2ccccc2)(c2ccc(C(F)(F)F)cc2)c2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.49
ACHE P22303 2/20 0.49
ALDH1A1 P00352 1/20 0.46
HSD11B1 P28845 4/20 0.43
FFAR1 O14842 1/20 0.42
CDK1 P06493 1/20 0.42
CCNB1 P14635 1/20 0.42
CCNA2 P20248 1/20 0.42
CDK2 P24941 1/20 0.42
CDK7 P50613 1/20 0.42
CCNH P51946 1/20 0.42
CCNA1 P78396 1/20 0.42
FFAR4 Q5NUL3 1/20 0.42
VDR P11473 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA5A P35218 1/20 0.39
CA9 Q16790 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3132919 1.00 BCHE (0.49) BCHEACHEALDH1A1HSD11B1FFAR1
SCHEMBL3136577 1.00 BCHE (0.49) BCHEACHEALDH1A1HSD11B1FFAR1
SCHEMBL3136049 1.00 BCHE (0.49) BCHEACHEALDH1A1HSD11B1FFAR1
SCHEMBL503702 0.92 HSD11B1 (0.45) ALDH1A1HSD11B1HTTCA1CA2
SCHEMBL3139775 0.92 HSD11B1 (0.45) ALDH1A1HSD11B1HTTCA1CA2
SCHEMBL3132687 0.92 HSD11B1 (0.45) ALDH1A1HSD11B1HTTCA1CA2
SCHEMBL3191570 0.90 HSD11B1 (0.40) BCHEACHEALDH1A1HSD11B1FFAR1
SCHEMBL3141444 0.89 BCHE (0.42) BCHEACHEALDH1A1HSD11B1FFAR1
SCHEMBL5410201 0.89 FFAR1 (0.43) BCHEACHEALDH1A1HSD11B1FFAR1
SCHEMBL5405422 0.89 FFAR1 (0.43) BCHEACHEALDH1A1HSD11B1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1676835-B1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT WAKO PURE CHEM IND LTD (JP) 2014-12-10 EP disclosed
US-7642368-B2 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-05 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed