Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | ABL2 | P42684 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | CTSE | P14091 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31435965 | 0.93 | FPR2 (0.40) | SRCEGFRABL1ABL2CTSD | |
| SCHEMBL31435997 | 0.93 | ALDH1A1 (0.45) | CTSDCTSEBACE1ALDH1A1GPR119 | |
| SCHEMBL30365373 | 0.91 | PDE4B (0.38) | SRCCTSDCTSEBACE1ALDH1A1 | |
| SCHEMBL31435966 | 0.89 | HCAR1 (0.46) | ABL1CTSDCTSEBACE1ALDH1A1 | |
| SCHEMBL31435934 | 0.81 | IRAK4 (0.44) | ALDH1A1GPR119IRAK4DDB1CRBN | |
| SCHEMBL27253665 | 0.80 | BACE1 (0.50) | SRCCTSDCTSEBACE1ALDH1A1 | |
| SCHEMBL28766351 | 0.80 | SRC (0.43) | SRCEGFRALDH1A1GPR119USP30 | |
| SCHEMBL28766353 | 0.80 | SRC (0.43) | SRCEGFRALDH1A1GPR119USP30 | |
| SCHEMBL2386252 | 0.79 | ALDH1A1 (0.45) | CTSDCTSEBACE1ALDH1A1GPR119 | |
| SCHEMBL22245129 | 0.78 | SRC (0.40) | SRCEGFRABL1ABL2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250019378-A1 | PYRROLE[2,3-B]PYRIDINE DERIVATIVES AS TYRO3 INHIBITORS | HALIA THERAPEUTICS INC (US) | 2025-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250019378-A1 | PYRROLE[2,3-B]PYRIDINE DERIVATIVES AS TYRO3 INHIBITORS | TYRO3, TH, TYR | SRC 23/4885EGFR 853/4885ABL1 128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.