Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | STK17B | O94768 | 1/20 | 0.46 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 11/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31436126 | 0.99 | STK17B (0.46) | ACHEBACE1STK17BSTK17ADRD2 | |
| SCHEMBL31436105 | 0.91 | DRD2 (0.47) | STK17BSTK17ADRD2ADORA2AADORA2B | |
| SCHEMBL31436045 | 0.88 | BRD4 (0.49) | BACE1STK17BSTK17ADRD2ADORA2A | |
| SCHEMBL31436068 | 0.87 | STK17B (0.43) | STK17BSTK17ADRD2ADORA2AADORA2B | |
| SCHEMBL31436111 | 0.85 | DRD2 (0.44) | ACHEBACE1STK17BSTK17ADRD2 | |
| SCHEMBL31436060 | 0.84 | STK17B (0.58) | STK17BSTK17AADORA2AADORA2BADORA1 | |
| SCHEMBL4743239 | 0.82 | ACHE (0.58) | ACHEBACE1DRD2SIGMAR1TDP1 | |
| SCHEMBL7220892 | 0.82 | DRD2 (0.55) | ACHEBACE1DRD2TDP1CHRM2 | |
| SCHEMBL485945 | 0.82 | DRD2 (0.55) | ACHEBACE1DRD2TDP1CHRM2 | |
| SCHEMBL31596990 | 0.81 | DRD2 (0.58) | ACHEBACE1DRD2SIGMAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025088570-A1 | IONIZABLE LIPIDS AND IONIZABLE LIPID NANOPARTICLES | CRISPR THERAPEUTICS AG (CH) | 2025-05-01 | — | — | WO | disclosed |