Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 11/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31436126 | 0.89 | STK17B (0.46) | STK17BSTK17ADRD2ADORA2AADORA1 | |
| SCHEMBL31436085 | 0.87 | ACHE (0.46) | STK17BSTK17ADRD2ADORA2AADORA1 | |
| SCHEMBL31436105 | 0.87 | DRD2 (0.47) | STK17BSTK17ADRD2ADORA2AADORA1 | |
| SCHEMBL31436045 | 0.85 | BRD4 (0.49) | STK17BSTK17ADRD2ADORA2AADORA1 | |
| SCHEMBL22699069 | 0.83 | DRD2 (0.54) | DRD2CACNA1HSIGMAR1TDP1 | |
| SCHEMBL31436060 | 0.82 | STK17B (0.58) | STK17BSTK17AADORA2AADORA1ADORA2B | |
| SCHEMBL31436077 | 0.78 | STK17B (0.42) | STK17BSTK17ADRD2ADORA2AADORA1 | |
| SCHEMBL31436112 | 0.77 | TDP1 (0.62) | STK17BSTK17AADORA2AADORA1ADORA2B | |
| SCHEMBL31436080 | 0.77 | TDP1 (0.58) | STK17BSTK17AADORA2AADORA1ADORA2B | |
| SCHEMBL31436059 | 0.76 | STK17B (0.62) | STK17BSTK17ADRD2ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025088570-A1 | IONIZABLE LIPIDS AND IONIZABLE LIPID NANOPARTICLES | CRISPR THERAPEUTICS AG (CH) | 2025-05-01 | — | — | WO | disclosed |