SCHEMBL14967672

SCHEMBL14967672

CCOC(=O)C1(c2ccc(OC)cc2)CO1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
KMT2A Q03164 4/20 0.43
GAA P10253 2/20 0.43
POLB P06746 3/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
LMNA P02545 5/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HPGD P15428 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CHRNA1 P02708 1/20 0.43
CHRNG P07510 1/20 0.43
CHRNB1 P11230 1/20 0.43
CHRNB2 P17787 1/20 0.43
CHRNB4 P30926 1/20 0.43
CHRNA3 P32297 1/20 0.43
CHRNA4 P43681 1/20 0.43
CHRND Q07001 1/20 0.43
KDM4E B2RXH2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14968165 0.88 CHRM1 (0.44) ALDH1A1KMT2AGAAPOLBCYP2C9
SCHEMBL14967816 0.87 ALDH1A1 (0.45) ALDH1A1KMT2APOLBLMNATDP1
SCHEMBL5166279 0.86 OPRM1 (0.51) KMT2ACYP2C9CYP2C19LMNATDP1
SCHEMBL14968157 0.85 ALDH1A1 (0.44) ALDH1A1KMT2APOLBLMNAABCB11
SCHEMBL9240911 0.84 F10 (0.44) ALDH1A1KMT2APOLBCYP2C19SMN1; SMN2
SCHEMBL7439116 0.84 ALDH1A1 (0.40) ALDH1A1KMT2AGAAPOLBCYP2C9
SCHEMBL21874235 0.84 LMNA (0.46) ALDH1A1KMT2AGAAPOLBCYP2C9
SCHEMBL21874111 0.84 ALDH1A1 (0.39) ALDH1A1KMT2AGAAPOLBCYP2C9
SCHEMBL7444252 0.84 ALDH1A1 (0.40) ALDH1A1KMT2AGAAPOLBCYP2C9
SCHEMBL14967988 0.84 ALDH1A1 (0.43) ALDH1A1LMNAABCB11MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
CN-104023996-B For the method for the polydiene and polydiene copolymer that prepare the cold flow with reduction 株式会社普利司通 2017-10-24 CN disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
CN-103555590-B Geotrichum candidum and its application in preparation of (2R, 3S)-ethyl phenyl glycidate UNIV ZHEJIANG TECHNOLOGY 2015-05-27 CN disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
CN-104023996-A METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP 2014-09-03 CN disclosed
CN-103555590-A Geotrichum candidum and its application in preparation of (2R, 3S)-ethyl phenyl glycidate UNIV ZHEJIANG TECHNOLOGY 2014-02-05 CN disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed