Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26637741 | 1.00 | LMNA (0.41) | LMNAMEN1KMT2AOPRM1ALDH1A1 | |
| SCHEMBL31685961 | 0.84 | LMNA (0.45) | LMNAMEN1KMT2AOPRM1ALDH1A1 | |
| SCHEMBL26637819 | 0.84 | LMNA (0.45) | LMNAMEN1KMT2AOPRM1ALDH1A1 | |
| SCHEMBL26637720 | 0.83 | OPRM1 (0.41) | OPRM1ALDH1A1OPRD1OPRK1SLC22A1 | |
| SCHEMBL31436608 | 0.83 | OPRM1 (0.41) | OPRM1ALDH1A1OPRD1OPRK1SLC22A1 | |
| SCHEMBL26638068 | 0.78 | OPRK1 (0.40) | MEN1KMT2AALDH1A1OPRK1SLC6A4 | |
| SCHEMBL26638121 | 0.78 | OPRM1 (0.42) | MEN1KMT2AOPRM1ALDH1A1OPRD1 | |
| SCHEMBL30477031 | 0.74 | LMNA (0.58) | LMNAOPRM1ALDH1A1OPRD1OPRK1 | |
| SCHEMBL31685947 | 0.73 | SLC6A2 (0.45) | LMNAMEN1KMT2AOPRM1ALDH1A1 | |
| SCHEMBL26637568 | 0.73 | SLC6A2 (0.45) | LMNAMEN1KMT2AOPRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119486999-A | Azetidine compounds, pharmaceutical compositions thereof, methods of preparation and their use in the treatment of CNS disorders | 伊科诺姆有限公司 | 2025-02-18 | — | — | CN | disclosed |