Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24571567 | 1.00 | NAMPT (0.46) | NAMPTPKMKMT2AALDH1A1KDM4E | |
| SCHEMBL24571700 | 0.92 | UTS2R (0.47) | NAMPTPKMKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL31437042 | 0.92 | UTS2R (0.47) | NAMPTPKMKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL24571898 | 0.91 | KMT2A (0.42) | NAMPTPKMKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL24571532 | 0.88 | NAMPT (0.52) | NAMPTPKMKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL24571634 | 0.88 | BRD4 (0.43) | NAMPTPKMKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29640988 | 0.86 | ALDH1A1 (0.50) | PKMKMT2AALDH1A1KDM4EEPHX2 | |
| SCHEMBL24711651 | 0.86 | PKM (0.54) | PKMKMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL24571940 | 0.85 | PKM (0.48) | NAMPTPKMKMT2AALDH1A1KDM4E | |
| SCHEMBL24571568 | 0.83 | CCR5 (0.48) | NAMPTPKMKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120152967-A | Bifunctional compounds containing 2, 5-substituted pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-119630644-A | Bifunctional compounds containing pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119630651-A | Bifunctional compounds containing substituted pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |