Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 5/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL31630905 | 0.91 | DDB1 (0.39) | DDB1CRBNALDH1A1HSD17B10KDM4E | |
| SCHEMBL27039415 | 0.91 | CRBN (0.46) | DDB1CRBNHTTDRD3HTR6 | |
| Trifluoroacetic Acid SCHEMBL31583715 | 0.86 | CRBN (0.37) | DDB1CRBNF10MAOAMAOB | |
| Trifluoroacetic Acid SCHEMBL31630892 | 0.85 | DDB1 (0.52) | DDB1CRBNMAOBALDH1A1HSD17B10 | |
| Trifluoroacetic Acid SCHEMBL31630912 | 0.83 | PKM (0.43) | DDB1CRBNLMNAABHD6DRD3 | |
| Trifluoroacetic Acid SCHEMBL30525331 | 0.83 | DDB1 (0.55) | DDB1CRBNALDH1A1PDK2HTT | |
| Trifluoroacetic Acid SCHEMBL31583511 | 0.83 | RAD52 (0.41) | DDB1CRBNF10MAOAMAOB | |
| SCHEMBL31437046 | 0.81 | CRBN (0.49) | DDB1CRBNF10ALDH1A1HSD17B10 | |
| SCHEMBL26641696 | 0.81 | HTR3E (0.43) | DDB1CRBNALDH1A1PDK2HTR3E | |
| SCHEMBL27023026 | 0.80 | NOTUM (0.44) | DDB1CRBNPDK2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119630644-A | Bifunctional compounds containing pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119630651-A | Bifunctional compounds containing substituted pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |