Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | MC5R | P33032 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5188507 | 0.84 | MAPT (0.38) | PARP1MAPTALDH1A1LMNAMC4R | |
| SCHEMBL30110406 | 0.84 | PARP1 (0.47) | PARP1MAPTALDH1A1LMNAMC4R | |
| SCHEMBL30165832 | 0.84 | ALDH1A1 (0.50) | PARP1MAPTALDH1A1LMNANR1H2 | |
| SCHEMBL31331999 | 0.84 | MAPT (0.40) | PARP1MAPTALDH1A1LMNANPSR1 | |
| SCHEMBL30080845 | 0.80 | NR1H2 (0.45) | PARP1MC4RMC5RNR1H2NR1H3 | |
| SCHEMBL30979323 | 0.80 | GPR119 (0.46) | PARP1NR1H2NR1H3 | |
| SCHEMBL30910354 | 0.80 | ALDH1A1 (0.39) | PARP1MAPTALDH1A1LMNAMC4R | |
| SCHEMBL3697218 | 0.80 | DPP4 (0.47) | PARP1MC4RMC5RNR1H2NR1H3 | |
| SCHEMBL25913721 | 0.80 | DPP4 (0.47) | PARP1MC4RMC5RNR1H2NR1H3 | |
| SCHEMBL29351957 | 0.80 | PARP1 (0.39) | PARP1MAPTALDH1A1LMNAMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119630644-A | Bifunctional compounds containing pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119630651-A | Bifunctional compounds containing substituted pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |