Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30910354 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MAPTLMNAPARP1NR1H2 | |
| SCHEMBL25913721 | 0.84 | DPP4 (0.47) | PARP1NR1H2NR1H3 | |
| SCHEMBL3697218 | 0.84 | DPP4 (0.47) | PARP1NR1H2NR1H3 | |
| SCHEMBL8147630 | 0.84 | MAPT (0.43) | ALDH1A1MAPTLMNAPARP1KDM4E | |
| SCHEMBL29351957 | 0.84 | PARP1 (0.39) | ALDH1A1MAPTLMNAPARP1 | |
| SCHEMBL31437077 | 0.84 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNA | |
| SCHEMBL31437059 | 0.84 | PARP1 (0.38) | ALDH1A1MAPTLMNAPARP1KDM4E | |
| SCHEMBL25279026 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAPDE5APKM | |
| SCHEMBL8140446 | 0.83 | PARP1 (0.43) | ALDH1A1MAPTPARP1NR1H2NR1H3 | |
| SCHEMBL1673503 | 0.83 | MEN1 (0.43) | ALDH1A1MAPTLMNAPARP1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557933-B | Bruton tyrosine kinase and mutant degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-115557933-A | Bruton tyrosine kinase and mutant degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2023-01-03 | — | — | CN | disclosed |