SCHEMBL6280141

SCHEMBL6280141

COC(=O)c1ccccc1OCCO

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 2/20 0.59
MAPT P10636 2/20 0.59
HTT P42858 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
SLC6A3 Q01959 4/20 0.57
SLC6A4 P31645 2/20 0.57
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
GAA P10253 1/20 0.57
ALDH1A1 P00352 5/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2C9 P11712 1/20 0.56
HPGD P15428 1/20 0.56
CYP2C19 P33261 1/20 0.56
KDM4E B2RXH2 4/20 0.54
GLA P06280 1/20 0.53
LMNA P02545 2/20 0.51
TSHR P16473 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19973714 0.92 MAPT (0.62) HSP90AA1MAPTHTTNPSR1SLC6A3
SCHEMBL4448505 0.89 MAPT (0.59) HSP90AA1MAPTHTTNPSR1SLC6A3
SCHEMBL385973 0.86 HSP90AA1 (0.59) HSP90AA1MAPTHTTNPSR1SLC6A3
SCHEMBL536427 0.86 MAPT (0.59) HSP90AA1MAPTHTTNPSR1SLC6A3
SCHEMBL4385291 0.86 SLC6A3 (0.57) HSP90AA1MAPTHTTNPSR1SLC6A3
SCHEMBL24571900 0.85 MAPT (0.49) HSP90AA1MAPTHTTNPSR1SLC6A3
SCHEMBL31437079 0.85 MAPT (0.49) HSP90AA1MAPTHTTNPSR1SLC6A3
SCHEMBL2389931 0.85 HSP90AA1 (0.58) HSP90AA1MAPTHTTNPSR1SLC6A3
SCHEMBL4051431 0.85 HSP90AA1 (0.58) HSP90AA1MAPTHTTNPSR1SLC6A3
SCHEMBL7981719 0.85 MAPT (0.62) HSP90AA1MAPTHTTNPSR1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024036600-A1 AUTONOMOUS PARTHENOGENETIC HAPLOID REPRODUCTION METHOD FOR MATERNAL CELLS AND USE THEREOF IN BREEDING 中国农业科学院作物科学研究所 2024-02-22 WO disclosed
CN-115786390-A Maternal cell autonomous parthenogenetic haploid reproduction method and breeding application thereof 中国农业科学院作物科学研究所 2023-03-14 CN disclosed
CN-108102313-B Dyed polyester master batch and production process thereof 苏州市苏宏塑料有限公司 2020-06-26 CN disclosed
CN-108102313-A A kind of dyeing polyester master batch and its production technology 苏州市苏宏塑料有限公司 2018-06-01 CN disclosed
US-20140271845-A1 COATED SUBSTRATE COMPOSITIONS CEROVENE, INC. (US) 2014-09-18 US disclosed
US-6846900-B2 POLYVALENT CARBOXYLIC ACID ESTER, PROCESS FOR PRODUCING THE CARBOXYLIC ACID ESTER, PLASTIC LENS COMPOSITION USING THE CARBOXYLIC ESTER, PLASTIC LENS OBTAINED BY CURING THE COMPOSITION AND PROCESS FOR PRODUCING THE PLASTIC LENS SHOWA DENKO K.K. (JP) 2005-01-25 US disclosed
US-20030144447-A1 Novel polyvalent carboxylic acid ester and their use in plastic lens compositions SHOW A DENKO K.K. (JP) 2003-07-31 US disclosed
US-4053415-A UNSATURATED POLYESTER ETHER HAVING A PHOTOCROSSLINKABLE MOIETY FUJI PHOTO FILM CO., LTD. (JA) 1977-10-11 US disclosed
US-3984379-A POLYMERIZATION CATALYSTS TEIJIN LIMITED (JA) 1976-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030144447-A1 Novel polyvalent carboxylic acid ester and their use in plastic lens compositions VCL, VIM, CRYAA HSP90AA1 3296/4885MAPT 143/4885HTT 406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.