SCHEMBL3143784

SCHEMBL3143784

c1ccc(-c2c(-c3ccccc3)c3cccnc3c3ncccc23)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.52
HSP90AA1 P07900 2/20 0.52
NPC1 O15118 1/20 0.52
TOP1 P11387 1/20 0.43
CCR1 P32246 3/20 0.42
CCR8 P51685 3/20 0.42
KDM4E B2RXH2 3/20 0.42
ENPP1 P22413 1/20 0.42
CKS1B P61024 1/20 0.41
GLO1 Q04760 1/20 0.41
SKP2 Q13309 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 3/20 0.41
MAPT P10636 2/20 0.41
GMNN O75496 1/20 0.41
TP53 P04637 1/20 0.41
MMP2 P08253 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
MMP9 P14780 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31026593 1.00 L3MBTL1 (0.52) L3MBTL1HSP90AA1NPC1TOP1CCR1
SCHEMBL1102824 0.87 L3MBTL1 (0.43) L3MBTL1HSP90AA1NPC1TOP1CCR1
SCHEMBL1103081 0.85 L3MBTL1 (0.42) L3MBTL1HSP90AA1NPC1TOP1KDM4E
SCHEMBL1103115 0.85 L3MBTL1 (0.42) L3MBTL1HSP90AA1NPC1TOP1KDM4E
SCHEMBL1103109 0.85 L3MBTL1 (0.42) L3MBTL1HSP90AA1NPC1TOP1KDM4E
SCHEMBL1103120 0.85 L3MBTL1 (0.42) L3MBTL1HSP90AA1NPC1TOP1KDM4E
SCHEMBL1102789 0.84 L3MBTL1 (0.41) L3MBTL1HSP90AA1NPC1TOP1KDM4E
SCHEMBL1102990 0.84 L3MBTL1 (0.41) L3MBTL1HSP90AA1NPC1TOP1KDM4E
SCHEMBL1102949 0.84 L3MBTL1 (0.41) L3MBTL1HSP90AA1NPC1TOP1KDM4E
SCHEMBL1103097 0.84 L3MBTL1 (0.41) L3MBTL1HSP90AA1NPC1TOP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735170-A1 METATHESIS COMPOSITIONS COMPRISING AIR-STABLE IMIDO ALKYLIDENE COMPLEXES Verbio SE (DE) 2026-05-06 EP disclosed
WO-2025003441-A1 METATHESIS COMPOSITIONS COMPRISING AIR-STABLE IMIDO ALKYLIDENE COMPLEXES VERBIO VEREINIGTE BIOENERGIE AG (DE) 2025-01-02 WO disclosed
US-20230389409-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-30 US disclosed
US-20230203072-A1 AIR-STABLE IMIDO ALKYLIDENE COMPLEXES AND USE THEREOF IN OLEFIN METATHESIS REACTIONS VERBIO SE (DE) 2023-06-29 US disclosed
US-20230203072-A1 AIR-STABLE IMIDO ALKYLIDENE COMPLEXES AND USE THEREOF IN OLEFIN METATHESIS REACTIONS VERBIO SE (DE) 2023-06-29 US disclosed
CN-101663265-B The manufacture method of aryl-hydroxy amine 和光纯药工业株式会社 2016-06-08 CN disclosed
US-8455690-B2 Method for producing arylhydroxylamine WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2013-06-04 US disclosed
US-20100113830-A1 METHOD FOR PRODUCING ARYLHYDROXYLAMINE WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-05-06 US disclosed
EP-2154125-A1 METHOD FOR PRODUCING ARYLHYDROXYLAMINE Wako Pure Chemical Industries, Ltd. (JP) 2010-02-17 EP disclosed
US-7491450-B2 Organic electroluminescent device CANON KABUSHIKI KAISHA (JP) 2009-02-17 US disclosed
US-7491450-B2 Organic electroluminescent device CANON KABUSHIKI KAISHA (JP) 2009-02-17 US disclosed
EP-0813608-B1 OSMIUM-CONTAINING REDOX MEDIATOR ROCHE DIAGNOSTICS CORP (US) 2002-09-04 EP disclosed
EP-0813608-A4 OSMIUM-CONTAINING REDOX MEDIATOR ROCHE DIAGNOSTICS CORP (US) 2000-02-09 EP disclosed
US-5846702-A Reagent including an osmium-containing redox mediator BOEHRINGER MANNHEIM CORPORATION (US) 1998-12-08 US disclosed
EP-0813608-A1 OSMIUM-CONTAINING REDOX MEDIATOR BOEHRINGER MANNHEIM CORPORATION (US) 1997-12-29 EP disclosed
US-5589326-A FOR ELECTROCHEMICAL BIOSENSORS BOEHRINGER MANNHEIM CORPORATION (US) 1996-12-31 US disclosed
WO-1996025514-A1 OSMIUM-CONTAINING REDOX MEDIATOR BOEHRINGER MANNHEIM CORPORATION (US) 1996-08-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203072-A1 AIR-STABLE IMIDO ALKYLIDENE COMPLEXES AND USE THEREOF IN OLEFIN METATHESIS REACTIONS SOD1, ZRANB2, ZNF277 L3MBTL1 1999/4885HSP90AA1 4328/4885NPC1 2068/4885
US-20100113830-A1 METHOD FOR PRODUCING ARYLHYDROXYLAMINE PAH, APEH, HPD L3MBTL1 1549/4885HSP90AA1 2119/4885NPC1 3771/4885
US-20230389409-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE L1CAM, NOM1, MSL1 L3MBTL1 12/4885HSP90AA1 4240/4885NPC1 1780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.