Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.63 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.63 |
| ▸ | AHR | P35869 | 3/20 | 0.56 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TAF1 | P21675 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30260903 | 1.00 | TNF (0.63) | TNFRIPK1AHRCMA1CYP2A6 | |
| SCHEMBL2535332 | 0.77 | TNF (0.59) | TNFRIPK1AHRCMA1CSNK2A1 | |
| SCHEMBL30622580 | 0.77 | TNF (0.59) | TNFRIPK1AHRCMA1CSNK2A1 | |
| SCHEMBL17659438 | 0.77 | AHR (0.52) | TNFRIPK1AHRCMA1CSNK2A1 | |
| SCHEMBL26978265 | 0.77 | AHR (0.52) | TNFRIPK1AHRCMA1CSNK2A1 | |
| SCHEMBL16341620 | 0.77 | AHR (0.52) | TNFRIPK1AHRCMA1CYP2A6 | |
| SCHEMBL4048611 | 0.77 | TNF (1.00) | TNFRIPK1AHRCMA1F7 | |
| SCHEMBL31058113 | 0.77 | TNF (0.59) | TNFRIPK1AHRCMA1CYP2A6 | |
| SCHEMBL18966966 | 0.77 | TNF (0.59) | TNFRIPK1AHRCMA1F7 | |
| SCHEMBL15662861 | 0.77 | TNF (0.59) | TNFRIPK1AHRCMA1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109704-A1 | 5-MEMBERED HETEROARYL INDAZOLE CGAS INHIBITORS AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2026-04-23 | — | — | US | disclosed |
| US-20260108509-A1 | 6-MEMBERED HETEROARYL INDAZOLE CGAS INHIBITORS AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2026-04-23 | — | — | US | disclosed |
| US-12543493-B2 | Organic light-emitting device | SFC CO., LTD. (KR) | 2026-02-03 | — | — | US | disclosed |
| EP-4650345-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF IN MEDICINE | Kangbaida (Sichuan) Biotechnology Co., Ltd. (CN) | 2025-11-19 | — | — | EP | disclosed |
| US-20250179079-A1 | HEXAHYDROPYRIDO[4,3-B]INDOLYL KETONE DERIVATIVES USEFUL AS CGAS MODULATORS | VENTUS THERAPEUTICS U.S., INC. (US) | 2025-06-05 | — | — | US | disclosed |
| WO-2025038863-A1 | INDOLE AND PYRROLOYPYRIDINE DERIVATIVES AS GPR17 MODULATORS | BIOGEN MA INC. (US) | 2025-02-20 | — | — | WO | disclosed |
| EP-4496796-A1 | HEXAHYDROPYRIDO[4,3-B]INDOLYL KETONE DERIVATIVES USEFUL AS CGAS MODULATORS | Ventus Therapeutics U.S., Inc. (US) | 2025-01-29 | — | — | EP | disclosed |
| US-12030900-B2 | Boron compound and organic light-emitting diode comprising same | SFC CO., LTD. (KR) | 2024-07-09 | — | — | US | disclosed |
| US-12030900-B2 | Boron compound and organic light-emitting diode comprising same | SFC CO., LTD. (KR) | 2024-07-09 | — | — | US | disclosed |
| US-20240196736-A1 | ORGANIC LIGHT-EMITTING DEVICE | SFC CO., LTD. (KR) | 2024-06-13 | — | — | US | disclosed |
| EP-0812826-A1 | 1H-indole and benzo(b)thiophene derivatives with 4-(1,2,3,6-tetra:hydro:pyridinyl)- and 4-piperidinyl-groups bound to the heterocyclic ring as inhibitors of serotonin reuptake | ELI LILLY AND COMPANY (US) | 1997-12-17 | — | — | EP | disclosed |
| US-5627196-A | ANTIDEPRESSANTS AND ANTISEROTONIN AGENTS | ELI LILLY AND COMPANY (US) | 1997-05-06 | — | — | US | disclosed |
| US-5614523-A | INDOLYLOXY COMPOUNDS | ELI LILLY AND COMPANY (US) | 1997-03-25 | — | — | US | disclosed |
| EP-0707581-B1 | INDOLINE DERIVATIVES AS 5HT2C ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1997-02-26 | — | — | EP | disclosed |
| US-5576321-A | ALKOXY-SUBSTITUTED INDOLES | ELI LILLY AND COMPANY (US) | 1996-11-19 | — | — | US | disclosed |
| CN-1129937-A | Indoline derivatives as 5HT2C antagonists | SMITHKLINE BEECHAM PLC (GB) | 1996-08-28 | — | — | CN | disclosed |
| WO-1996022290-A1 | COMPOUNDS HAVING EFFECTS ON SEROTONIN-RELATED SYSTEMS | ELI LILLY AND COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |
| EP-0722941-A2 | Compounds having effects on serotonin-related systems | ELI LILLY AND COMPANY (US) | 1996-07-24 | — | — | EP | disclosed |
| EP-0707581-A1 | INDOLINE DERIVATIVES AS 5HT 2C? ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001976-A1 | INDOLINE DERIVATIVES AS 5HT2C ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179079-A1 | HEXAHYDROPYRIDO[4,3-B]INDOLYL KETONE DERIVATIVES USEFUL AS CGAS MODULATORS | CGAS, XDH, NPY1R | TNF 2911/4885RIPK1 1449/4885AHR 1945/4885 |
| US-20260109704-A1 | 5-MEMBERED HETEROARYL INDAZOLE CGAS INHIBITORS AND USES THEREOF | CGAS, GBA3, CYP11B2 | TNF 4843/4885RIPK1 4354/4885AHR 1228/4885 |
| US-12543493-B2 | Organic light-emitting device | CRY1, CRY2, AOC2 | TNF 4051/4885RIPK1 3109/4885AHR 19/4885 |
| US-20240196736-A1 | ORGANIC LIGHT-EMITTING DEVICE | AOX1, CRY2, SUN2 | TNF 490/4885RIPK1 2117/4885AHR 49/4885 |
| US-20260108509-A1 | 6-MEMBERED HETEROARYL INDAZOLE CGAS INHIBITORS AND USES THEREOF | CGAS, GBA3, GBA1 | TNF 4834/4885RIPK1 4211/4885AHR 1104/4885 |
| US-12030900-B2 | Boron compound and organic light-emitting diode comprising same | CLTB, CD79B, CYBA | TNF 1319/4885RIPK1 1975/4885AHR 656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.