Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10914678 | 0.78 | ALDH1A1 (0.72) | ALDH1A1KMT2AMEN1PRMT5WDR77 | |
| SCHEMBL31439480 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1PRMT5WDR77 | |
| SCHEMBL31439562 | 0.76 | KMT2A (0.52) | ALDH1A1KMT2AMEN1PRMT5WDR77 | |
| SCHEMBL15624932 | 0.70 | ALDH1A1 (0.82) | ALDH1A1KMT2AMEN1PRMT5WDR77 | |
| SCHEMBL5052482 | 0.69 | KDM4E (0.77) | ALDH1A1KMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL10502377 | 0.69 | KMT2A (1.00) | ALDH1A1KMT2ATSHRMAPK10HSD17B10 | |
| SCHEMBL5067157 | 0.69 | KMT2A (0.61) | ALDH1A1KMT2ATSHRMAPK10SMN1; SMN2 | |
| SCHEMBL8354036 | 0.68 | MAPK10 (0.51) | ALDH1A1KMT2AMEN1TSHRMAPK10 | |
| SCHEMBL3378228 | 0.68 | ALDH1A1 (0.67) | ALDH1A1KMT2AMEN1PRMT5WDR77 | |
| SCHEMBL10679600 | 0.67 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025015167-A2 | ERASTIN KETONE ANALOGS AND USES THEREOF | EXARTA THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | disclosed |